Clinical Presentation Symptoms and Labs/Imaging initial analysis from the outbreak in China (n=44,000) The majority of infections were in 30-70 year olds Disease Severity – 1.2% asymptomatic, 80% mild 20% severe disease (testing started after outbreak and may underestimate asymptomatic) Symptoms: • Fever 43.8%(eventually in 80%) • Cough 67.8% (Sputum 33.7%) • Fatigue 38.1% • Shortness of Breath 18.7% • Myalgia/Arthralgia 14.9% • Sore throat 13.9% • Headache 13.4% v Lab/imaging: • Lymphocytopenia (<1500) 83.2% • CRP > 10 60.7% • CXR abnormality 59% (most commonly bilateral or local patchy shadowing) Other reported Symptoms • Reports of anosmia in as high as 30-50% of patients (anecdotal reports) 3/23/20 In a small study while diarrhea and sinusitis were seen all patients with those symptoms also had cough however one patient had just rhinitis and otitis with no other symptoms Cough 7/9, Fever 2/9, Diarrhea (2/9 both had cough and fever) , sinusitis 4/9 (all had cough), rhinitis (2/9, 1 also with otitis 1 with cough), Asymptomatic 1/9 (n=9 Germany) 3/15/20 possible signal that diarrhea may be more common than previously thought in presentation